Artificial sweeteners, how healthy are they? This is the question that one needs to ask if the person is a regular consumer of sweeteners. It may turn out that it causes weight gain as compared to weight loss. Brian Hoffmann, assistant professor in the Department of Biomedical Engineering at the Medical College of Wisconsin and Marquette University, and a lead author of the study said that artificial sweeteners come with their disadvantages.
They are a very contentious topic as far as health and nutrition are concerned. But their presence is so strong in the society that that individual himself is attempting to solve the jigsaw puzzle of what actually is going on. Depending on rats and human cell cultures, Hoffman and his team discovered numerous pathways connecting artificial sweeteners with catabolic alterations at the genetic level which could eventually lead to diabetes and obesity.
Particularly the researchers found that three weeks subjection to aspartame and acesulfame potassium, two artificial sweeteners often integrate in products such as Equal changed the pronouncement of certain genes assertion of specific genes accountable for lipid metabolism in the cells of both rats and humans.
Hoffmann said that Aspartame had some important alterations one being increase in lipids in the bloodstream and a slowdown of biomolecule that includes clearing lipids from the bloodstream. The same applies to acesulfame potassium.
He further added that they took these specific sweeteners and put them on endothelial cells, the cells that line the blood vessels and would be open to them in the body and they distinguished an important debilitated proposing why sweeteners and diet soda have been connected to possible cardiovascular issues.